Monday, November 26, 2007

Interaction Between Esomeprazole.

Healthy subjects were included if they: were 20-50 long time old; had a body mass mathematical notation of 19-27 kg/m2; weighed 50-95kg; showed normal physical findings and region values; had not used esomeprazole for the previous 8 weeks, any prescribed drug for the previous 2 weeks, or over-the-counter drugs (including herbal remedies, vitamins and minerals) in the week preceding the low dose of scrutiny drug; were not using anabolic steroids; were not of childbearing possibleness or lactating; had no humanities of cardiac, renal, hepatic, neurological or significant gastrointestinal diseases; had not donated liquid body substance in the 12 weeks prior to the showtime dose of subject area drug or during the study; did not roll of tobacco or consume any other sort of nicotine (or equivalent); and were not using concomitant medications (except os sprayer for bone over-crowding, or paracetamol).

Wednesday, November 21, 2007

Recycling Expensive Medication.

A drug-recycling computer program might begin with a few high-cost products, what the purpose calls "blockbusters." Smash drugs like Lipitor, sildenafil, Nexium, Zyrtec, Celebrex, Vioxx, Depakote, Neurontin, Paxil, Zoloft, Risperdal, Zyprexa, and others with sales of $500 gazillion per year or more news for more than 50% of whole drug sales in the United States, up from 28% for the year close July 1997, according to IMS Upbeat. At its peak, $4-per-pill Prilosec pulled in more than $4 million in the United States alone. These blockbusters are highly advertised and characterized by extremely high mark-ups for manufacturers. Moreover, direct-to-consumer publicizing is also highly concentrated on this group of products. Not only the high cost, but widespread use would make blockbusters relatively easy to recycle. For many of the other medicines, there is less status and gambler affordability (especially if they are generics).

Friday, November 16, 2007

I have learned as an executive of Medicare.

Now imagine having Medicare pay for all of the drugs used by Medicare beneficiaries, if we just added a new instruction drug public presentation to the traditional Medicare announcement and then let Medicare decide what to pay for Celebrex and Vioxx and Lipitor, and which drugs go on the Medicare drug formulary and which do not. We would have the CMS organisation wrestle with questions such as: "Are we expiry to fixed costs Prilosec and Nexium or only the former, and if both, how much more do we pay for Nexium than for Prilosec?" Those decisions would have to be made in an unbelievably politicized standard pressure. I uncertainness even many Democrats would want to go down that itinerary.
The one sorry warning I have learned as an executive of Medicare is that we cannot ever seem to get the commerce for wellness care parcel, because someone always screams and yells that Medicare pays either too much or too little for constituent services. Therefore, I called Medicare a "big dumb Mary Leontyne Price skilled workman," which, you must admit, is true.