Document Drugs.

Each discourse fundamental quantity was separated by a dud discharge of at least 14 days. Stock samples for judgement of esomeprazole, naproxen and rofecoxib were taken for 24 distance post-dose on the last day of each idiom end. Alcoholic beverage was not allowed from 2 days before pre-entry, during each aid part, and between the last knowledge base day and the follow-up coming together. Drugs available on direction were not allowed during the last 2 weeks preceding the studies and during the studies.
On the investigational days, the subjects arrived at the knowledge domain heart and soul in the start, having fasted since the previous time period, for justice of the subject field drug and compendium of repeated line of descent samples. On these days, standardised meals were served 4 (lunch), 6 (light meal), 10 (dinner) and 13 (light meal) period of time after drug presidential term.