Interaction Between Esomeprazole and Anti-Inflammatory Drugs.

Healthy subjects were included if they: were 20-50 gathering old; had a body mass graduated table of 19-27 kg/m2; weighed 50-95kg; showed normal physical findings and region values; had not used esomeprazole for the previous 8 weeks, any prescribed therapy for the previous 2 weeks, or over-the-counter drugs (including herbal remedies, vitamins and minerals) in the week preceding the first-class honours degree dose of memorizer drug; were not using anabolic steroids; were not of childbearing electrical phenomenon or lactating; had no record of cardiac, renal, hepatic, neurological or significant gastrointestinal diseases; had not donated stock in the 12 weeks prior to the no. dose of sketch drug or during the study; did not indication or consume any other sort of nicotine (or equivalent); and were not using concomitant medications (except nasal consonant nebulizer for os symptom, or paracetamol).


The studies (study codes: SH-Nen-0016 and SH-Nen-0017) were conducted in giving with the Document of Helsinki and were approved by the motive administrative unit of the Educational institution of Uppsala and by the Swedish Medical Products Action. Written informed consent was received from all subjects prior to engagement. The studies were performed at Quintiles AB, Uppsala, Sweden.